641two types of autoimmune disease so let us recap in case of systemic autoimmune diseases the incriminating antigens and the autoimmunity are distributed in many tissues. The issues pertaining to immunological disease classification are compounded by the absence of a precise definition of what constitutes autoinflammation in the common polygenic diseases.
Autoimmunity is the system of immune responses of an organism against its own healthy cells and tissues.
Classification of autoimmune diseases pdf. Any disease that results from such an aberrant immune response is termed an autoimmune diseaseprominent examples include celiac disease diabetes mellitus type 1 henloch scholein pupura hsp sarcoidosis systemic lupus erythematosus sle sjogrens syndrome eosinophilic. R o s e n m d e d itors 340 a n eng l j m ed v ol. Microbiology module autoimmunity and autoimmune diseases microbiology 578 notes fig.
Autoimmune diseases are divided into two groups. Autoimmune disorders can overlap. Autoimmunity and autoimmune disease autoimmune mechanisms underline many diseases some organ specific others systemic in distribution.
Request pdf types of autoimmune disorders. M a c k a y m d a n d f r e d s. There are more then 80 autoimmune diseases occurring in 5 6 of the.
Or more than one systemic disease. Several diseases and disorders are caused by autoimmune mechanisms. Atrophic gastritis of autoimmune type leads to pernicious anemia ulcerative colitis ibd uc crohns disease ibd c food protein intolerance enteropathies such as gluten sensitive enteropathy gse celiac disease celiac sprue nervous system.
Quality and quantity of the autoimmune response. Demyelinating diseases eg multiple sclerosis amyotrophic lateral sclerosis sensor motor. Classification in autoimmune diseases the immune system attacks self antigens.
An individual may have more than one organ specific disorder. Autoimmune diseases autoimmune disorders are a broad spectrum of disease that can affect any part of the body. This is in contrast to polygenic autoimmune disease where a broad consensus on a generic definition exists.
345 n o. Genetic factors such as hla type are important in autoimmune disease and it is. The organ specic autoimmune diseases in which the target antigens and the tissue dis orders are localized in one organ and the systemic autoimmune diseases in which the response to a certain type of antigens that are.
R eview a rticles a d va n ces in im m u n olog y i a n r. Autoimmune diseases can generally be divided into those that are systemic and those that are localised and only affect a certain. Inflammation is the classic sign of autoimmunity although how this impacts on an individual is determined by which part of the body is affected.
More than 80 have been identified a considerable number with similar symptoms. Autoinflammation may simply be defined as self.